Marianne Williamson, the self-help author and spiritual advisor who ran unsuccessfully for the 2020 Democratic presidential nomination, will run again in 2024, she told supporters this weekend.

“Since the 2016 election, it’s strange that anyone thinks they can know who can win the presidency,” he said in a statement emailed to supporters and posted on facebook. “And I’m not going to put myself through this again just to add to the conversation. I’m running for president to help close an aberrational chapter in our history and help usher in a fresh start.” He added: “Washington is full of good political auto mechanics, but the problem is we’re on the wrong track.”

You will formally announce your campaign in a Saturday speech.

Four years ago, Ms. Williamson was one of more than 25 contenders for the nomination ultimately won by Joseph R. Biden Jr. This time, so far, she is the only candidate, entering the 2024 race even before Biden has done so, although he is expected to run for re-election.

Ms. Williamson, 70, became famous in the self-help world as the author of several best-selling books and as a spiritual advisor to Oprah Winfrey. In the 1980s, she founded the Los Angeles and Manhattan Centers for Life, which supported people with HIV and AIDS, and Project Angel Food, which provides free meals to people with serious illnesses.

A signature proposal in his first presidential campaign was to establish a federal Peace Department, which would pursue nonmilitary solutions to foreign conflicts and efforts abroad to combat domestic extremism, including white supremacy. He also supported reparations for slavery, arguing in a Democratic debate that it was better described not as “financial assistance” but as “payment of a debt that is owed.”

But what stood out to him most were his spiritual pronouncements, particularly his statement that Trumpism was a symptom of a disease in the American psyche that could not be cured by political policies.

On a Democratic debate stage in 2019, spoke directly to then-President Donald J. Trump: “Mr. President, if you’re listening, I want you to listen to me please: you have harnessed fear for political purposes, and only love can drive it out.” He added: “I’m going to love the harness for political purposes. And lord, love will win.”

In the 12 months of her last presidential campaign, from January 2019 until she dropped out of the race in January 2020, before the first votes were cast, Ms. Williamson never surpassed low single-digit polling averages. After leaving her, she endorsed Senator Bernie Sanders of Vermont.

Ms. Williamson has promoted dubious or discredited medical theories, particularly on mental illness. In books, interviews, and social media posts before and during his 2020 campaign, he described clinical depression as a “scam,” argued that antidepressants were recklessly overprescribed, and suggested without evidence that they might have been to blame. some celebrity suicides.

In an interview with The New York Times in 2019, he said he regretted the “scam” description and was not categorically opposed to antidepressants. But he largely stood by his claims that they were overused and potentially dangerous, including in a message posted on Twitter after designer Kate Spade committed suicide: “How many public figures on antidepressants have to hang themselves before the FDA do something, Big Pharma? cops to what you know, and the average person stops falling for this?

There was no public evidence that Ms. Spade was taking antidepressants. The Food and Drug Administration has found no evidence of an increased risk of suicidal thoughts with antidepressant use in people older than 24, and untreated depression is a major risk factor for suicide.

Ms Williamson also drew attention in 2019 for calling vaccine mandates “Orwellian,” a reference to vaccines against diseases like measles and polio that most school-age children are long due for. Within days, she apologized for sounding “as if she questions the validity of life-saving vaccines,” but she said it was reasonable to suspect the motives of pharmaceutical companies.

Public skepticism of science and medicine has only grown since then, coalescing into a political force with major public health consequences. Many politicians, mainly Republicans, have fanned it, including Mr. Trump, who is running again in 2024, and the governor. Ron DeSantis of Florida, a potential candidate.

In Twitter posts since 2020, Ms. Williamson has supported a strong government response to the pandemic, said she was vaccinated against covid and strongly rejected descriptions of herself as anti-vaccination, but called vaccine mandates “a legitimate civil rights issue for a lot of people.”